Liver & digestion

Immune health

Hepatitis C (anti-HCV)

What it measures

Viral Hepatitis

Clinical significance

The diagnosis of hepatitis C virus (HCV) infection currently relies on the detection of antibody to HCV (anti-HCV). However, anti-HCV positivity may indicate past infection, current infection or possibly non-specific reactivity.

Normal range for this assay is "Not Detected." The quantitative range of this assay is 10 -100,000,000 IU/mL (1.0 -8.0 log IU/mL).

What is the most accurate test for HCV?

The HCV Ab test is used for initial screening for hepatitis C. The test is performed by enzyme immunoassays (EIAs), which detect the presence of hepatitis C antibodies in serum. The result of the test is reported as positive or negative. Third-generation EIAs have a sensitivity/specificity of approximately 99%.

Why do I have hep C antibodies but no virus?

You can still test positive for hepatitis C antibodies, but not have an active case of hepatitis C. In certain cases, your body can completely clear the virus on its own. You will need a second test, called an RNA or viral load test, to see whether hepatitis C is active in your body.

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